Diffuse ST depression with ST elevation in aVR on a 12-lead ECG

Horizontal ST depression across many leads, deepest in V4-V6, I and II, with ST elevation in aVR (bigger than any in V1): global subendocardial ischemia, not a territory.

What to look for

The ST is down in most leads and up in aVR. That aVR elevation is the mirror image of all the depression, not injury under aVR, so this is not a STEMI territory. It's ischemia of the inner layer of the whole ventricle, and it doesn't point to one artery. Sometimes it's severe left main or three-vessel disease, but far more often it's supply and demand: a tachycardia, bleeding, sepsis, hypotension, severe hypertension. Treat the driver, report it as diffuse ST depression with ST elevation in aVR, and take the patient somewhere with a cath lab. Mortality is high even though it's usually not an occlusion.

Examples

Each is a standard 12-lead: 2.5 seconds of each lead in four columns, with 10 seconds of lead II along the bottom, drawn to scale (25 mm a second, 10 mm a millivolt). The measurements are under each one.

Example 1 · 12-lead · 10 seconds
IaVRV1V4IIaVLV2V5IIIaVFV3V6II25 mm/s · 10 mm/mV
Rate
119/min
Rhythm
RegularSinus: upright in II, biphasic in V1, one before every QRS
PR
0.15 s
QRS
0.10 s, narrow
Axis
82°, normal
QTc
0.43 s
ST up
aVR
ST down
I, II, aVL, aVF, V2, V3, V4, V5, V6
T inverted
None (apart from aVR)
Also
Smaller ST elevation (under the STEMI cut-off) in V1 · Pathological Q waves (40 ms or wider) in aVL
Example 2 · 12-lead · 10 seconds
IaVRV1V4IIaVLV2V5IIIaVFV3V6II25 mm/s · 10 mm/mV
Rate
114/min
Rhythm
RegularSinus: upright in II, biphasic in V1, one before every QRS
PR
0.18 s
QRS
0.10 s, narrow
Axis
45°, normal
QTc
0.42 s
ST up
aVR
ST down
I, II, aVL, aVF, V2, V3, V4, V5, V6
T inverted
None (apart from aVR)
Also
Smaller ST elevation (under the STEMI cut-off) in V1

Don't confuse it with

The ECG tool in the app gives you a new 12-lead every time and walks you through reading it: rate, QRS, axis, then where the ST is up and down. It's part of the Paramedic level, and you can try 5 ECGs a day free.

Try the 12-lead drill

Where the criteria come from

Others in the look-alikes and other findings group