Digoxin effect on a 12-lead ECG

A sagging, scooped ST depression (the reverse tick) where the R waves are tall, flattened T waves and a short QT. It means the patient takes digoxin, not that they're toxic.

What to look for

Digoxin at ordinary doses changes the ECG on purpose-free days too: a downsloping, sagging ST depression that curves back up (the reverse tick, or Salvador Dali's moustache), mostly where the R waves are tall, flattened or biphasic T waves, and a short QT. That's the effect, and on its own it only tells you the patient takes the drug. Toxicity shows up as rhythm trouble: frequent PVCs, bradycardia, AV block, atrial tachycardia with block, regularized AF, bidirectional VT.

Examples

Each is a standard 12-lead: 2.5 seconds of each lead in four columns, with 10 seconds of lead II along the bottom, drawn to scale (25 mm a second, 10 mm a millivolt). The measurements are under each one.

Example 1 · 12-lead · 10 seconds
IaVRV1V4IIaVLV2V5IIIaVFV3V6II25 mm/s · 10 mm/mV
Rate
81/min
Rhythm
RegularSinus: upright in II, biphasic in V1, one before every QRS
PR
0.20 s
QRS
0.10 s, narrow
Axis
34°, normal
QTc
0.36 s
ST up
aVR
ST down
I, II, aVF, V3, V4, V5, V6
T inverted
None (apart from aVR)
Also
Smaller ST elevation (under the STEMI cut-off) in V1
Example 2 · 12-lead · 10 seconds
IaVRV1V4IIaVLV2V5IIIaVFV3V6II25 mm/s · 10 mm/mV
Rate
86/min
Rhythm
RegularSinus: upright in II, biphasic in V1, one before every QRS
PR
0.20 s
QRS
0.09 s, narrow
Axis
58°, normal
QTc
0.37 s
ST up
aVR
ST down
I, II, aVF, V3, V4, V5, V6
T inverted
None (apart from aVR)
Also
Smaller ST elevation (under the STEMI cut-off) in V1

Don't confuse it with

The ECG tool in the app gives you a new 12-lead every time and walks you through reading it: rate, QRS, axis, then where the ST is up and down. It's part of the Paramedic level, and you can try 5 ECGs a day free.

Try the 12-lead drill

Where the criteria come from

Others in the Electrolytes, drugs and temperature group